In this story Steve Rogers gets defrosted as usual by everybody is extra uncomfortable/afraid around him because Steve is an alpha and those are dreadfully rare. Also it might be because the serum amped up Steve's hormons/instincts up to the max, which makes everybody think he is a second away from being uncontrollably agressive or violent.
Meanwhile Steve wonders why everybody is so weird/afraid around him even though he tries to downplay his 'old fashioned' behaviour.
There might have been a bit about Nick Fury being extra careful around Captain America.
Many thanks in advance for the help.