1. It was pretty big. Can't remember if there were a lot of chapters, or if they were just long. And it was unfinished last I saw.
2. Tony, Clint (and Barney), and Phil had all at a point where they were children, been dosed with the super soldier serum, but it never does the same thing to each person. Later Betty Ross is also dosed by her father.
3. Steve collapses at some point because he isn't eating enough.
4. There is a wedding for Bruce and betty on the Hellicarier.
5. Tony secretly has an actual medical degree, and an alterego to go along with it.
That's all I got folks. Can anyone help? I don't recall pairings, sorry.